|
rs2072621
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Women heterozygous for rs13440581, had a 1.6-fold increased risk of baseline depression, while the odds of depression comorbid with anxiety were increased fourfold for women homozygous for the minor allele of rs2072621.
|
25798330 |
2015 |
|
rs13440581
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Women heterozygous for rs13440581, had a 1.6-fold increased risk of baseline depression, while the odds of depression comorbid with anxiety were increased fourfold for women homozygous for the minor allele of rs2072621.
|
25798330 |
2015 |
|
rs242941
|
|
|
0.020 |
GeneticVariation |
BEFREE |
When all subjects were grouped based on family history of mental illness, there was a statistically significant association of CRHR1 rs242941 with family history regardless of depression status (P = 0.043).
|
26518448 |
2015 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We therefore examined whether the single-nucleotide polymorphism producing a valine-to-methionine substitution at codon 66 (val66met) of the BDNF gene was associated with childhood NE, in the context of parental depression and relationship discord.
|
20921572 |
2010 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We therefore examined whether the single-nucleotide polymorphism producing a valine-to-methionine substitution at codon 66 (val66met) of the BDNF gene was associated with childhood NE, in the context of parental depression and relationship discord.
|
20921572 |
2010 |
|
rs53576
|
|
|
0.090 |
GeneticVariation |
BEFREE |
We tested whether the rs53576 polymorphism in the oxytocin receptor (OXTR) gene accounts for variation in the impact of low social support as a risk factor for depression among mothers during the perinatal period.
|
30928624 |
2019 |
|
rs14259
|
|
|
0.020 |
GeneticVariation |
BEFREE |
We tested in the 200 Italians families for evidence of linkage of the PSMD9 single nucleotide polymorphisms (SNPs) IVS3+nt460 A > G, IVS3+nt437 T > C and E197G A > G with the depression phenotype.
|
22934761 |
2012 |
|
rs765798193
|
|
|
0.020 |
GeneticVariation |
BEFREE |
We tested in the 200 Italians families for evidence of linkage of the PSMD9 single nucleotide polymorphisms (SNPs) IVS3+nt460 A > G, IVS3+nt437 T > C and E197G A > G with the depression phenotype.
|
22934761 |
2012 |
|
rs6267
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We stratified PD by status of depression and the association between COMT rs6267</span> "GT" genotype and pain severity remained significant (P < 0.01).
|
28740224 |
2017 |
|
rs334558
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We observed a triple interaction of 5-HTTLPR, rs334558 and treatment on severity of depression.
|
22119086 |
2012 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We investigated the independent and interactive effects of BDNF methylation and val66met polymorphism on late-life depression.
|
25648279 |
2015 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We investigated the independent and interactive effects of BDNF methylation and val66met polymorphism on late-life depression.
|
25648279 |
2015 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We investigated the effect of brain-derived neurotrophic factor (BDNF) Val(66)Met polymorphism on the severity of depressive and anxiety symptoms in never-smokers, former smokers, non-dependent, and nicotine-dependent smokers with a current diagnosis of depression and/or anxiety.
|
25618300 |
2015 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We investigated the effect of brain-derived neurotrophic factor (BDNF) Val(66)Met polymorphism on the severity of depressive and anxiety symptoms in never-smokers, former smokers, non-dependent, and nicotine-dependent smokers with a current diagnosis of depression and/or anxiety.
|
25618300 |
2015 |
|
rs1799983
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We investigated the association between the three polymorphisms of the endothelial nitric oxide synthase (eNOS) gene (single-nucleotide polymorphism (SNP); rs2070744, rs1799983, variable number tandem repeat (VNTR) in intron 4) and scores on the Hamilton Rating Scale for Depression, plasma metabolites of NO (NO(x) ) or ankle brachial index in patients with MDD and healthy controls.
|
22031268 |
2011 |
|
rs2070744
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We investigated the association between the three polymorphisms of the endothelial nitric oxide synthase (eNOS) gene (single-nucleotide polymorphism (SNP); rs2070744, rs1799983, variable number tandem repeat (VNTR) in intron 4) and scores on the Hamilton Rating Scale for Depression, plasma metabolites of NO (NO(x) ) or ankle brachial index in patients with MDD and healthy controls.
|
22031268 |
2011 |
|
rs139315125
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We identified two rare variants in the circadian clock gene PERIOD3 (PER3-P415A/H417R) in humans with familial advanced sleep phase accompanied by higher Beck Depression Inventory and seasonality scores. hPER3-P415A/H417R transgenic mice showed an altered circadian period under constant light and exhibited phase shifts of the sleep-wake cycle in a short light period (photoperiod) paradigm.
|
26903630 |
2016 |
|
rs34637584
|
|
|
0.030 |
GeneticVariation |
BEFREE |
We identified one heterozygous G2019S mutation in a PD patient who also suffered from obsessive disorder and depression and presented hallucinations and delusional jealousy while he was treated with l-dopa, pramipexole, and amantadine.
|
18621566 |
2009 |
|
rs4994
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We hypothesized that the Trp64Arg polymorphism may be associated with increased risk of schizophrenia and depression.
|
22609474 |
2012 |
|
rs1220000453
|
|
|
0.020 |
GeneticVariation |
BEFREE |
We have investigated the possible use of both CNTF null-mutation and BDNF polymorphism C270T as biomarkers for depression in the Vienna Transdanube Aging (VITA) study.
|
16797081 |
2006 |
|
rs4880
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We found that the T/T genotype of the c.47T>C polymorphism was linked with an increased risk of depression.
|
29331597 |
2018 |
|
rs4680
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We found that the COMT val158met polymorphism was not associated with 4-week fluoxetine therapeutic response; however, association analysis showed that patients with the COMT(Val/Val) genotype had poorer responses in the eighth week (CLUMP T1 P=0.020) and consistently showed significantly smaller reductions in HAM-D(21) scores in the eighth week (P=0.027).
|
18533273 |
2009 |
|
rs6318
|
|
|
0.030 |
GeneticVariation |
BEFREE |
We found that psychosocial stress was associated with both depression and BMI, but that Cys23Ser was not directly associated with, nor did it modify the associations of psychosocial stress with depression or BMI.
|
30333852 |
2018 |
|
rs10988134
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We found that only the A/A genotype of c.*456G > A - KAT1 (rs10988134) increased the risk of depression occurrence.
|
29777939 |
2018 |
|
rs1082214
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We found significant association between TIMELESS variants and depression with fatigue (D+FAT+) (rs7486220: pointwise P = 0.000099, OR = 1.66; corrected empirical P for the model of D+FAT+ = 0.0056; haplotype 'C-A-A-C' of rs2291739-rs2291738-rs7486220-rs1082214: P = 0.0000075, OR = 1.72) in females, and association to depression with early morning awakening (D+EMA+) (rs1082214: pointwise P = 0.0009, OR = 2.70; corrected empirical P = 0.0374 for the model D+EMA+; haplotype 'G-T' of rs7486220 and rs1082214: P = 0.0001, OR = 3.01) in males.
|
20174623 |
2010 |